You can also opt for the Power Play multiplier, for a small additional cost of $1.00 per line. Once you have selected the numbers you want, your ticket for America’s biggest lottery is in! US Powerball – Rules of the GameĪs per the official Powerball rules, for each line you play, choose 5 main numbers from a guess range of 1 to 69 and a Powerball from 1 to 26. Find out everything you need to know about how to play Powerball and put in your ticket for the chance to scoop some of the largest jackpots in the entire lottery market.